Ziv Ben-Zion

Clinical Neuroscientist

Unraveling PTSD: Symptom cluster change during and 1 year after veterans' residential PTSD treatment.


Journal article


Georgina M Gross, Tobias R Spiller, Ziv Ben-Zion, Ariel Rubenstein, R. H. Pietrzak, O. Duek, Rani A Hoff, I. Harpaz-Rotem
Psychological Trauma, 2024

Semantic Scholar DOI PubMed
Cite

Cite

APA   Click to copy
Gross, G. M., Spiller, T. R., Ben-Zion, Z., Rubenstein, A., Pietrzak, R. H., Duek, O., … Harpaz-Rotem, I. (2024). Unraveling PTSD: Symptom cluster change during and 1 year after veterans' residential PTSD treatment. Psychological Trauma.


Chicago/Turabian   Click to copy
Gross, Georgina M, Tobias R Spiller, Ziv Ben-Zion, Ariel Rubenstein, R. H. Pietrzak, O. Duek, Rani A Hoff, and I. Harpaz-Rotem. “Unraveling PTSD: Symptom Cluster Change during and 1 Year after Veterans' Residential PTSD Treatment.” Psychological Trauma (2024).


MLA   Click to copy
Gross, Georgina M., et al. “Unraveling PTSD: Symptom Cluster Change during and 1 Year after Veterans' Residential PTSD Treatment.” Psychological Trauma, 2024.


BibTeX   Click to copy

@article{georgina2024a,
  title = {Unraveling PTSD: Symptom cluster change during and 1 year after veterans' residential PTSD treatment.},
  year = {2024},
  journal = {Psychological Trauma},
  author = {Gross, Georgina M and Spiller, Tobias R and Ben-Zion, Ziv and Rubenstein, Ariel and Pietrzak, R. H. and Duek, O. and Hoff, Rani A and Harpaz-Rotem, I.}
}

Abstract

OBJECTIVE Although treatment of posttraumatic stress disorder (PTSD) is effective in reducing symptom severity, remission rates are low. One potential underlying reason for treatment ineffectiveness is differential response of specific PTSD symptom clusters. Using data from a national Veterans Affairs (VA) residential PTSD treatment cohort, we conducted a longitudinal study to examine changes in Diagnostic and Statistical Manual of Mental Disorders, fifth edition PTSD symptom clusters from admission to 1-year follow-up.

METHOD PTSD symptom data were analyzed from a national cohort of veterans who completed VA PTSD residential treatment between October 2019 and September 2020 (n = 1,648; 13% women; median age 44.2 years). Endorsement (%) and severity (M[SD]) of PTSD clusters and individual symptoms were compared at admission, discharge, 4-month and 1-year follow-ups.

RESULTS Large magnitude reductions in all four PTSD symptom clusters were observed from admission to discharge and both follow-ups; however, endorsement of all symptom clusters remained high. Intrusions (Cluster B) were the most highly endorsed at discharge and follow-up, whereas avoidance symptoms (Cluster C) were the least highly endorsed. Differential patterns of change were observed among the 20 individual PTSD symptoms; for example, flashbacks decreased during treatment, but increased to near admission levels by 1-year postdischarge.

CONCLUSIONS Results suggest that intrusive symptoms may be more resistant to residential treatment for PTSD and contribute to lower likelihood of treatment success. Future work is needed to examine differential treatment response for PTSD clusters, to inform the improvement of current and creation of novel treatment interventions, and to better address intrusive symptoms to maximize PTSD treatment gains. (PsycInfo Database Record (c) 2024 APA, all rights reserved).